The city's tally of homicides this year reached 13 on Thursday.
A man, believed to be in his 20s, was found dead on Garner Avenue, Buffalo police said. His name was not released.
The man, who was apparently shot, was found in a backyard on Garner, between Grant and Herkimer streets, on the city's West Side.
Officers from the police department's Northwest District were called to the scene and found the man's body at about 10 a.m. Homicide detectives are investigating.
Police ask anyone with information to call or text the department's confidential tip line at 847-2255.