As the Bills entered the 2018 season, just 12 players remained from the 2016 roster, built by former General Manager Doug Whaley and ex-coach Rex Ryan. Just three players from the years 2010 to 2016 who were "drafted by Whaley" while he was GM or the right-hand man to Buddy Nix were still on the team at the start of 2018 – John Miller, Shaq Lawson and Adolphus Washington.
The 12 has been cut to five following tight end Charles Clay's release Friday.
The five remaining:
- Linebacker Lorenzo Alexander, who just signed a one-year extension.
- Long-snapper Reid Ferguson, who just signed a three-year contract.
- Defensive end Jerry Hughes, who has one season remaining on his contract.
- Linebacker Shaq Lawson, who has one season remaining with the Bills having to decide whether to pick up his fifth-year option.
- Running back LeSean McCoy, who has one season remaining on his contract.
The seven who began 2018 with the Bills and are either no longer on the roster or a pending free agent.
- Tight end Charles Clay, who was released.
- Offensive lineman Ryan Groy, who is a pending free agent.
- Offensive lineman John Miller, who is a pending free agent.
- Offensive lineman Jordan Mills, who is a pending free agent.
- Defensive tackle Adolphus Washington, who was released in early September and played in four games with the Bengals.
- Defensive tackle Kyle Williams, who retired after the season.
- Tight end Logan Thomas, who is a pending restricted free agent.