Nathan Peterman's first starting assignment will be knotty.
The Buffalo Bills are switching to their rookie quarterback for a road game. Three hours away, no less.
Ten-year veterans have trouble adapting to playing in the Pacific time zone. Peterman must prepare for the Los Angeles Chargers in four days, one of which will be spent on an airplane.
One of the most significant victories in Buffalo sports history happened in San Diego, where the Bills beat the Chargers in 1965 for a second straight AFL title.
Since then, results have been flaccid out yonder.
The Super Bowl-bound 1992 Bills were 9.5-point favorites against the Los Angeles Raiders in the Coliseum. Todd Marinovich outperformed Jim Kelly in a 20-3 Bills defeat.
Buffalo has played 56 regular-season games in the Pacific time zone yet has won only 17 of them.
The Bills have been betting favorites out West seven times, but have gone 3-4. They've been in 26 pick 'em matchups, going 9-16-1.
The Bills are 1-2 all-time in Western playoff games. Three months after losing to Marinovich and the Raiders, the Dallas Cowboys vaporized the Bills, 52-17, in Super Bowl XXVII.
Since the NFL adopted the current playoff format in 1990, teams from the Eastern time zone are 8-16 while visiting the Pacific time zone in the postseason.
That record is shaded because the opponent with the better record hosts that playoff game. The home team is considered superior. Factor in betting expectations and Eastern teams are 11-13 against the spread when playing three time zones away.
As you'd expect, the Bills have been lousy on Pacific time during their playoff drought.
Since 2005, the Bills are 1-7 in the Pacific time zone and have given up an average of 35.3 points a game while scoring 17.9 points.
Throughout their playoff drought, the Bills are 4-10. The worst losses were by scores of 45-3 at San Francisco, 37-10 at San Diego, 48-10 at San Diego and 35-0 at San Francisco.
So it would seem to be an added impediment for Peterman that he's getting his first NFL start on the other side of the continent.
Although there weren't any rookie-QB-debut variables, Bills coach Sean McDermott's teams have been successful on Pacific time.
Over his nine seasons on Andy Reid's staff with the Philadelphia Eagles, they were 6-2 when playing out West, although 1-2 when McDermott was defensive coordinator.
The Carolina Panthers went 4-2 on Pacific time with McDermott as their defensive coordinator.
"We've put a lot of time into research into the science behind the two-day trip, the one-day trip, the practices," McDermott said. "This goes all the way back to the summer, really, of trying to get ahead of it and doing the proper research to put our players in the position to play and perform."
McDermott said that Monday, the same day he announced Tyrod Taylor would remain his starter.