The second quarter mirrored the first quarter: The Saints gained 132 yards of offense and scored on both of their possessions while the Bills punted three times and trailed 17-3 at the break.
Saints quarterback Drew Brees completed 15 of 20 passes for 146 yards in the first half, good for an average of 7.3 yards per play, while the Tyrod Taylor and the Bills were the inverse of the Saints, gaining 48 yards on 13 attempts, or 3.7 yards per attempt.
Mark Ingram scored his second rushing touchdown of the first half on a 3-yard plunge with 9:08 to go. The Bills at least held in the red zone of the Saints' next drive, forcing a 23-yard field goal to keep the game within 14 points.
Rally history: The last time the Bills rallied to win when down by 14 points or more was their 17-14 win against the Lions in 2014. The Bills carried defensive coordinator Jim Schwartz off the field on their shoulders after the game.
Lasco hurt: Saints running back Daniel Lasco was injured after making a special teams tackle on Brandon Tate following Ingram's touchdown and had to be taken off the field in an ambulance. He was transported to a local hospital with a spinal injury, although the team said he has feeling in his extremities.