The Bills went three-and-out after receiving the second-half kickoff, but their second drive was flawless.
Tyrod Taylor began by rolling out left and throwing a 31-yard strike to Nick O'Leary, who made a nice catch on the sideline. LeSean McCoy gained 7 yards on a run, and then Taylor followed it up by hitting Jordan Matthews in stride on a deep crossing route for 25 yards. On the fourth play of the drive, Taylor threatened to run but then hit Charles Clay for a touchdown, giving the Bills a 20-16 lead.
E.J. Gaines picked off Trevor Siemian on the Broncos' ensuing possession and set the Bills up 32 yards from the end zone, but penalties and a sack moved the Bills 13 yards backward and they had to punt.
The Bills' red zone defense held once again earlier in the quarter, forcing the Broncos into a 28-yard field goal. Lorenzo Alexander had a important play on the drive, moving into the neutral zone after a Broncos' lineman flinched to draw a false start penalty, which changed the situation to a third and 12 just before the field goal.
Say what? Taylor and Clay struggled to connect for most of last season, which was well-documented, but things clicked in December and the pair has been hot ever since. Clay's touchdown gave him six in his last seven games – the most in the NFL since Week 14 of last year, though someone could pass him later.