This week in college football is all about Lamar Jackson against Clemson's ferocious defense loaded with former five-star recruits. Buffalo Bills fans, though, have plenty more to monitor with the 2018 draft in mind.
Two of the nation's best edge-rushers take the field in nationally televised games, and you can get a good look at some top-level wideouts throughout the day.
Of course, the L.A. boys -- Sam Darnold and Josh Rosen -- will be featured.
These are the college football games to watch this weekend for Bills fans:
- UCLA at Memphis, noon (ABC)
Prospects to watch: UCLA QB Josh Rosen, TE Caleb Wilson
Rosen is on national television for the entire East Coast to see in the afternoon. Even in his rather disappointing start to the season, the UCLA quarterback orchestrated -- along with Lady Luck -- an epic comeback against Texas A&M on Labor Day weekend. He was magnificent in an easy game against Hawaii a week ago, throwing for five touchdowns. The Bruins should face a more difficult test against Memphis on the road. Wilson is his favorite target and has impressive yards-after-the-catch ability.
- Oklahoma State at Pittsburgh, noon (ESPN)
Prospects to watch: Oklahoma State QB Mason Rudolph, WR James Washington; Pittsburgh WR Jester Weah
Another top signal-caller prospect playing a game in the early slate. Rudolph has been downright unfair to begin the season, as he's tossed six touchdowns with no interceptions and completed nearly 73 percent of his passes. Fortunately for him, the sturdy speedster Washington is also on Oklahoma State's roster. The two seemingly connect for three or four big-gainers per contest.
Speaking of pass-catchers who pose a formidable downfield threat, Pittsburgh's Weah is one of the more underrrated wideouts in college football. The 6-foot-3 receiver averaged a ridiculous 24.2 yards per catch in 2016. While he's been held under 11 yards per grab thus far in 2017, his combination of speed, size, and ability to win in jump-ball situations makes him a player who can change the game on one play.
- SMU at TCU, 3:30 p.m. (ESPN U)
Prospect to watch: SMU WR Courtland Sutton
Sutton probably would have gone in the first or second round in the 2016 draft, but decided to stay at SMU to improve his skill set and bolster his draft stock. The 6-foot-4 wideout looks like Brandon Marshall on the field: a large, muscular presence. He has been a major point-producer for the Mustangs during his career in Dallas. He has five scores through two games in 2017, and had 19 touchdowns in 2015 and 2016 combined.
- Notre Dame at Boston College, 3:30 p.m. (ESPN)
Prospects to watch: Notre Dame OG Quenton Nelson; Boston College DE Harold Landry
Not necessarily a "marquee" quarterback game for Bills fans to watch. The Bills don't seem to be in the market for an elite-level guard, but you never know. Plus, Richie Incognito isn't a rookie. Nelson is a freight-train on the interior and will be the latest in a line of quality, pro-ready linemen Notre Dame has recently sent to the NFL.
Landry led college football in sacks last season and has an interesting matchup with Fighting Irish left tackle Mike McGlinchey, another top prospect.
- LSU at Mississippi State, 7 p.m. (ESPN)
Prospects to watch: LSU DE Arden Key
The Return of Arden Key. I put that in caps, because it's that important. Especially in Louisiana. I wouldn't be surprised if fans in Baton Rouge have that on a T-shirt this week. Key has some Myles Garrett to him. While he may not be as thick as the 2017 No.1 overall pick, he displayed a more explosive get-off in his sophomore season in 2016. A shoulder injury kept Key out of the first two outings of 2017. Now the 6-foot-6 freak is ready to step back on the field.
- Oregon at Wyoming, 7 p.m. (CBSSN)
Prospects to watch: Wyoming QB Josh Allen
Allen gets another shot against a quality Division I opponent from a power conference. The Iowa game went not so well. Oregon is athletic on defense, but has fallen on some tough times. Allen has a rocket arm, above-average athleticism, and a gunslinger mentality.
- Texas at USC, 7:30 p.m. (FOX)
Prospects to watch: USC QB Sam Darnold, RB Ronald Jones II, WR Deontay Burnett; Texas LB Malik Jefferson
Welcome to another edition of the Sam Darnold Show, live from the Los Angeles Coliseum. Darnold's dazzled for the vast majority of his first two games of his redshirt sophomore season, yet has tossed a few questionable interceptions. He'll get a Longhorns defense that was gashed by Maryland in an embarrassing opening-week loss, yet blanked San Jose State in Week Two.
Jefferson, a young, fluid inside linebacker, will face his most difficult test of the season. Jones II has proven to be extraordinarily difficult to corral in the run game. Burnett has been a dynamic play-maker at all levels of the field thus far, too. USC is loaded.
- Clemson at Louisville, 8 p.m. (ABC)
Prospects to watch: Louisville QB Lamar Jackson, WR Jaylen Smith; Clemson DL Clelin Ferrell, DL Austin Bryant, DT Christian Wilkins, LB Kendall Joseph, LB Dorian O'Daniel
Here's your run-of-the-mill, mid-September game that features probably five or six future first-round picks. Jackson has looked like an NFL quarterback in his first two games -- something that wasn't true last year when he won the Heisman. Smith is the recipient of many of Jackson's passes, and the 6-foot-3 wideout's been able to make an impact in the intermediate area and down the field. He has 17 grabs to begin the year.
Clemson has become an NFL factory. Hats off to you, Dabo Swinney. The Tigers have the most talented defensive front seven in college football. Defensive ends Ferrell and Bryant were dominant against Auburn last week. Defensive tackle Wilkins is a pass-rushing spark plug bound to hear his named called in Round One. Behind them, Joseph and O'Daniel are twitchy, explosive linebackers ready to pounce on ball-carriers if they happen to make it past the line of scrimmage.