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Bills could be down several big pieces vs. Dolphins

Following Wednesday's practice, it seems the Bills could be without several important players for Sunday's game at Miami.

Running back LeSean McCoy, who's second in the NFL in rushing yards, left practice early with tightness in his hamstring, coach Rex Ryan said.

Meanwhile, Robert Woods – the Bills No. 1 receiver with Sammy Watkins on injured reserve – was still wearing a walking boot on his right foot/ankle in the locker room.

To top it off, defense tackle Marcell Dareus missed another practice with his hamstring injury and seems unlikely to make his season debut this week, saying he and the trainers are still "working our way to" running full speed.

"We're really trying not to have a relapse," said Dareus, who was seen riding an exercise bike during practice. "So we're slowly working things in, implementing just kind of getting out of the stance and so on and so forth. We're taking it slow, but at the same time we're just making sure we don't fall backwards."

As for McCoy, Ryan announced his ailment with the injury report following practice and took questions after having already given his usual Wednesday press conference before practice.

"He was tight in the hamstring, so we’ll see what happens with our medical evaluation and all that," Ryan said.

Asked about McCoy's availability for Sunday, Ryan said, "I’m not going to look into it, but we’ll see how he comes back.”

“We feel good about the guys that we do have," Ryan said, "but that’s assuming he won’t play. We’ll see how it goes.”

McCoy briefly left Sunday's game against the 49ers with a knee injury but was able to return. Ryan said that injury wasn't related to the hamstring injury he picked up Wednesday.

McCoy was limited last season by a hamstring injury suffered during the preseason. He later told reporters he had a Grade II strain before sitting out two games to get closer to 100 percent.

Reggie Bush said he didn't know McCoy got hurt during practice until he saw it on television in the locker room. Mike Gillislee, the team's No. 2 running back, said he wasn't worried about McCoy missing time.

"LeSean, he’ll be OK. He’ll be good," Gillislee said. "Not at all [worried]. But if he’s not, I’ll just step up, me and the other running backs."

Woods went the to locker room with a trainer just before halftime Sunday but was able to finish the game. He's listed as having a foot injury and said Wednesday "something down there gave out" while he was running a route. He said the injury wasn't new Sunday, but was something he had been dealing with.

"I'm not worried about it," Woods said, breaking into a smile that was strangely large for someone in a walking boot. "I'm just trying to rehab as much as I can and get back out there as fast as I can."

Wednesday's full injury report:

Did not participate: Dareus (hamstring), tight end Charles Clay (ankle), left tackle Cordy Glenn (ankle), Linebacker Lerentee McCray (knee), Woods (foot), and tackle Seantrel Henderson (back).

Limited: Cornerback Corey White (shoulder), tackle Cyrus Kouandjio (ankle), cornerback Kevon Seymour (shoulder), center Patrick Lewis (knee), McCoy (hamstring) and fullback Jerome Felton (back).

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