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Dareus doesn't practice, could miss sixth game for Bills

Buffalo Bills defensive tackle Marcell Dareus, who was unable to return from a four-game suspension for substance abuse against the Los Angeles Rams last Sunday because of a pulled hamstring, didn't practice Wednesday because of the injury and said he didn't know whether he would play this Sunday against the San Francisco 49ers.

"I'm working with the trainers and we're trying to put it together and see what we can do," Dareus said. "Trying to work my way into running."

He said he was "walking around the field pretty good," but still feeling soreness and stiffness.

Dareus said the injury occurred last Friday when he "tried to crank it up and turn it on big time" while chasing backup quarterback EJ Manuel.

"I  just caught a flat tire out of nowhere," he said. "It happens. Big guys normally don't pull their hamstrings, but when they got a lot of power like me, (stuff) happens."

Linebacker Zach Brown, who leads the NFL with 58 tackles, also didn't practice because of a foot injury. Coach Rex Ryan said he didn't have any long-term concerns about Brown's status, but added, "With all these guys, we're going to see how it progresses during the week. Hope he's ready, though. We think he's going to be fine."

Linebacker Brandon Spikes and running back Mike Gillislee both were held out of practice due to illness, Ryan said.

Tight end Charles Clay was given his usual day off, according to the coach, to rest his knee. Outside linebacker Lorenzo Alexander, the league leader with seven sacks, was given the day off from practice to rest. Ryan said Jerry Hughes, the Bills' other outside linebacker, would have Thursday off from practice.

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