The hamstring injury Bills defensive tackle Marcell Dareus picked up in Friday's practice will keep him from making his season debut Sunday against the Rams, per ESPN's Adam Schefter.
Bills DT Marcell Dareus, back from four-game suspension, unlikely to play today due to hamstring injury he suffered in practice, per source.
— Adam Schefter (@AdamSchefter) October 9, 2016
Meanwhile, running back LeSean McCoy – who is questionable with a hand injury from Friday's practice – will play, per Schefter and NFL Network's Ian Rapoport.
McCoy said as much Friday, telling SportsCenter he "wouldn't miss [the game] for the world."
— Ian Rapoport (@RapSheet) October 9, 2016
The Bills will formally submit their inactive list an hour and a half before kickoff.