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Grants totaling $33.8 million announced for Roswell Park research

Roswell Park Cancer Institute researchers have received eight recent grants totaling $33.8 million from National Institutes of Health, Rep. Brian Higgins, D-Buffalo, announced Wednesday.

The grants will fund work on developing new approaches for treating prostate and head and neck cancers, improving response to immunotherapy and radiation, documenting tobacco use and supporting a software engineering project to analyze genomic data. The funds go toward five new research projects and three existing ones.

The research includes an ongoing Population Assessment of Tobacco and Health Study, a long-standing effort to document and interpret tobacco use in the U.S.; development of the Bioconductor Project, an open-source software system that provides tools for high throughput analysis of genomic data; novel imaging methods and treatments for oral/head and neck cancers; vitamin D as a safe strategy to enhance targeted chemotherapeutics; imaging methods to study how radiation affects salivary gland function; work on heat-shock proteins to improve cancer therapy; and a new combination therapy to prevent prostate cancer recurrence by accentuating a unique metabolic stress in prostate cells.