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Tyler Dunne's Points After: Bills 27, Colts 14

We'll have more from Ralph Wilson Stadium soon but the Buffalo Bills blasted the Indianapolis Colts, 27-14, at Ralph Wilson Stadium Sunday.

A few quick notes...

What it means: The takeaway? Buffalo's off-season moves paid off. The Bills took a hatchet to their offensive personnel at every position. QB. RB. TE. WR. OG. For the most part, the first impression was a smashing success. Percy Harvin, often initiating the offense in motion, caught five passes for 79 yards. Buffalo gained 150 yards on the ground (pre-kneeldowns). Charles Clay found room in the secondary. And, of course, Tyrod Taylor delivered in his first NFL start. He didn't force anything and provided the big play when Buffalo needed it. The team's new starter completed 14 of 19 passes for 195 yards with a touchdown.

Player of the Game: Tyrod Taylor. The Bills want speed. At running back, at receiver, on defense, everywhere. So why not at quarterback? In the season opener, Taylor was everything former coaches and teammates said he would be. He perfectly placed a 51-yarder to Percy Harvin up the right sideline on the first touchdown of the season, and also ran for a 31-yarder that set up the second score. The offense's tempo was crisp and deliberate with Taylor pushing all of the right buttons. Was the 15th time the charm for Buffalo?

Play of the Game: Karlos Williams' burst. The rookie out of Florida State will have a role on this offense after his 26-yard touchdown in the first half that gave Buffalo a 17-0 lead. He's 6-1, 230 with 4.48 speed and brings that all to the field. He had a team-high 55 yards on the ground, carrying defenders on his back a couple carries.

Rough debut: He didn't have a lot of running room to work with, but it wasn't a good start for the Bills' top back. LeSean McCoy finished with 41 yards on 17 attempts. When he bounced wide, he was corralled. Inside, there wasn't much wiggle room. Granted, McCoy did have one 12-yard touchdown called back on a Matthew Mulligan hold, but Williams did more with his carries.

Stat of the Game: 63.6, Andrew Luck's passer rating. Rex Ryan kept the Colts quarterback guessing all game long, unleashing timely blitzes. The combination of Ryan's pressure and the noise posed problems all game. Maybe most impressive was the play on the back end. Ronald Darby had his first career interception and Stephon Gilmore had arguably one of his best games as a Bill with four pass break-ups. Tight in coverage, he closed on the ball and played with physicality.

Early injury report: The Bills lost starting safety Corey Graham the first play of the game with a possible concussion. Both Bacarri Rambo (Graham's replacement) and Ronald Darby left the game with injuries. Rambo returned, Darby did not. Thrown in action, cornerback Mario Butler responded. He broke up the Luck pass that Aaron Williams picked off late to seal the win.

Coming up: Tom Brady and the New England Patriots. It'll be loud at The Ralph again.

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