Long-term and frequent use of aspirin is associated with significantly decreased risk of cervical cancer, according to a study led by researchers at Roswell Park Cancer Institute and published recently in the Journal of Lower Genital Tract Disease.
Aspirin use was associated with a 47 percent reduced risk of cervical cancer among frequent users – those who used aspirin seven or more times a week, regardless of duration – and 41 percent reduced risk among long-term frequent users – those with five or more years of frequent use.
Acetaminophen use was not associated with decreased risk of cervical cancer. A research team led by Kirsten Moysich, professor of oncology in the Department of Cancer Prevention and Control at Roswell, reported the results from the first U.S.-based study to examine the association between regular use of aspirin or acetaminophen.
The study examined 328 patients with cervical cancer and 1,312 controls, matched on age and decade, who enrolled in a hospital-based case-control study drawn from 26,831 patients who received treatment at Roswell Park Cancer Institute and completed the Patient Epidemiology Data System questionnaire between 1982 and 1998.
“Further research is needed,” Moysich said, “on the role of daily, long-term use of aspirin and acetaminophen as both cervical cancer chemopreventive agents and enhancement to standard treatment strategies post-diagnosis.”
According to the American Cancer Society, 12,900 new cases of cervical cancer will be diagnosed and 4,100 women will die from the disease this year.