Sept. 1918: The Red Sox win their fifth World Series in 15 years.
Jan. 1920: Red Sox owner/theatre producer Harry Frazee sell Babe Ruth to the Yankees for $125,000 cash and a $300,000 loan. Frazee used the money to fund his new Broadway show, "No, No, Nanette."
1921: In his first two seasons with the Yankees, Ruth rewrote the record book for power hitters, hitting 54 in 1920 and 59 in 1921.
1923: The newly built Yankee Stadium opens to 74,000 fans and would be known as "The House that Ruth Built." The Yanks also win their first of 27 World Series titles.
1941: Boston's Ted Williams hit .406 but finishes second to Yankees center fielder Joe DiMaggio in the MVP voting.
1946: The Red Sox lose the World Series to the St. Louis Cardinals in seven games. Williams hits just .200.
1949: Yankees edge out Red Sox in last two games of season to win the Pennant.
1967: The Red Sox lose another World Series to the St. Louis Cardinals in seven games.
1973: With the score tied 2-2 in the top of the ninth, Yankee catcher Thurman Munson attempted to score from third on a missed bunt attempt. Munson ran over Red Sox catcher Carlton Fisk, and a fight broke out between the two. The Red Sox went on to win the game 3-2 in the bottom of the ninth.
1976: Yankee outfielder Lou Piniella crashes into Red Sox catcher Carlton Fisk feet first and a brawl breaks out with Piniella and Fisk fighting at home plate. Boston pitcher Bill Lee and Yankee third baseman Graig Nettles are on the undercard.
1978: The Boston Massacre. The Yankees who trailed by as many as 14 games in the middle of July, swept the Red Sox in a four-game series at Fenway Park to tie Boston for first. The Bombers outscored the Sox 42-9.
1978: The Yankees and Red Sox faced off in a one-game playoff for the AL East title. Shortstop Bucky Dent hit a three-run home run in the seventh to lead the Yankees to victory. New York would go on to win their 22nd World Series.
1986: With Boston one strike away from winning it all, Bill Buckner's costly Game 6 error gives the Mets new life. The Red Sox would go on to lose the World Series in seven games.
1992: Fan favorite Wade Boggs switches sides and signs with the Yankees after 11 seasons in Beantown.
1999: In their first postseason meeting, the Yankees win the ALCS four games to one. Game 3 featured the highly anticipated matchup between Pedro Martinez and former Red Sox ace Roger Clemens. Boston won 13-1. The Yankees would go on to win their 25th World Series title.
Dec. 2002: Red Sox president Larry Lucchino labeled the Yankees the "Evil Empire" after Cuban free agent Jos Contreras opted to sign with the Yankees instead of the Red Sox.
2003: After Pedro Martinez hit Karim Garcia, Roger Clemens throws high to Manny Ramirez causing both benches to clear. During the brawl Yankees bench coach Don Zimmer charged at Martinez, who grabbed the 72-year-old and swung him to the ground.
2003" Up 5-2 in the eighth inning of Game 7, Red Sox manager Grady Little decided to leave starter Pedro Martinez in the game. Martinez proceeded to let the Yankees tie the game, then Aaron Boone led off the 11th inning with a solo home run off Tim Wakefield, ending the game and series.
Feb. 2004: Alex Rodriguez, after being courted by the Red Sox for nearly three months, was traded from Texas to the Yankees. Boston had a deal in place to acquire Rodriguez in December, but the players union rejected the changes made to ARod's contract.
July 2004: After Alex Rodriguez was hit by a Bronson Arroyo pitch, a fight broke out broke out between Rodriguez and Varitek. A bench-clearing brawl ensued, and both players were ejected. Bill Mueller hit a walk-off home run off Yankees closer Mariano Riveria to give the Red Sox the win.
Oct. 2004: Entering the ninth inning of Game 4 of the ALCS leading 4-3 and three outs away from sweeping the Red Sox four games to none. Boston's Kevin Millar walked to lead off the inning, pinch runner Dave Roberts Stole second and scored on Bill Mueller's single. The Red Sox then won the game on a David Ortiz home run in the bottom of the 12th.
Oct. 2004: Ortiz was the hero again, this time hitting a single in the bottom of the 14th to win Game 5. The game lasted five hours and 49 minutes.
Oct. 2004: With blood soaking through his sock thanks to pre-game ankle sutures, Boston's Curt Schilling pitched seven one-run innings to help the Red Sox win Game 6 of the ALCS and become the first team to force a Game 7 after being down three games to none.
Oct. 2004: Johnny Damon hit two home runs in a 10-3 Boston win in Game 7 of the ALCS as the Red Sox became just the third team in major North American sports history to win a seven-game series after trailing three games to none.
Oct. 2004: The Red Sox win their first World Series in 86 years, sweeping the Cardinals four games to none. The title ended the "Curse of the Bambino," which alleged that Boston after selling Babe Ruth to New York would never win another World Series.
Dec. 2005: Red Sox outfielder Johnny Damon, a fan-favorite during his four years in Boston, signed a four-year, $52 million contract with the Yankees.
Oct. 2007: The Red Sox sweep the Colorado Rockies to win their second World Series title in four years.
Oct. 2008: Gino Castignoli, a Red Sox fan working on the construction of the new Yankees Stadium, buried David Ortiz Red Sox jersey under what was going to become the visitor's dugout. The Yankees exhumed the jersey and donated it to the Jimmy Fund, a Boston-based charity long associated with the Red Sox.
Dec. 2008: The Yankees signed first baseman Mark Teixeira to an eight-year, $180 million contract. In the days leading up to the contract, the Red Sox appeared to be on the verge of acquiring Teixeira, but the Yankees offered more money at the last minute.
Oct. 2009: The Yankees win their 27th World Series title, while the Red Sox went on to lose in the ALDS to the Los Angeles Angels.