Broncos QB Jay Cutler: If the game is meaningful for Denver (meaning Kansas City wins its 1 p.m. game), he should thrive against the 49ers, who rank 27th against the pass (224.1 yards per contest).
Redskins RB Ladell Betts: Has five consecutive 100-yard games going into Saturday's game against the Giants, rushing for 678 yards on 136 carries. In the last two games, New York foes have run wild - 97 yards by Philadelphia's Brian Westbrook, and 126 by Reggie Bush and 108 by Deuce McAllister of New Orleans.
Panthers WR Steve Smith: Was shut out last week in Atlanta but goes against the Saints, who have given up an NFL-high 16 receptions of 40 yards or more.
Cardinals QB Kurt Warner: Has been sacked 13 times in 136 pass attempts and is on the road to face the Chargers, who lead the league with 60 sacks.
Bills RB Willis McGahee: On the road to face the Ravens, who rank second in rushing defense (78.3 ypg) and have yielded an NFL-low five rushing touchdowns, including just one at M&T Bank Stadium.
Titans WR Drew Bennett: Hasn't caught a pass in the last two games and faces the Patriots, who have surrendered the fewest touchdown receptions (10) in the league.
- Tom Borrelli