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Bristol-Myers Squibb Co. has eliminated the jobs of 70 scientists, chemical engineers, managers and support staff at its facilities in New York and New Jersey as it begins to align manufacturing operations for its new portfolio of medicines.

The majority of the job cuts took place Tuesday in East Syracuse, but cuts were also made in New Brunswick, N.J. Company spokesman Robert Hutchinson would not provide a breakdown.

Bristol announced in August that it would cut 120 jobs over the next two years as it ends antibiotics manufacturing. The company is in transition from manufacturing to research, Hutchinson said.

The company will still employ 800 people in East Syracuse, where it has a technology center. Bristol has spent $60 million to expand its biologics drug-making capabilities since 2001 and another $50 million to expand its laboratories in East Syracuse.