Ben Roethlisberger, Steelers, threw two touchdown passes in a 27-3 win over Philadelphia. He has won his first six career starts, matching the longest streak by a rookie quarterback in the NFL since 1970. Mike Kruczek was 6-0 for the Steelers in 1976 while filling in for an injured Terry Bradshaw.
Drew Brees, Chargers, threw four touchdown passes during a 43-17 rout of New Orleans. He has 18 TD passes this season and only three interceptions.
Jake Plummer, Broncos, threw for four scores without an interception in a 31-13 victory over Houston.
Rod Smith, Broncos, set team records for career receptions and TD catches during the win over Houston. After making his 676th catch, he later grabbed his 56th touchdown toss -- Smith moved past Shannon Sharpe in both categories.
Antonio Gates, Chargers, caught three TD passes during the win over New Orleans. The last San Diego tight end to grab three touchdown tosses was Kellen Winslow in 1983.
Santana Moss, Jets, caught six passes for 157 yards and a touchdown in New York's 22-17 loss to Buffalo.
Michael Pittman, Buccaneers, scored on a team-record 78-yard run. He finished with three touchdowns and 128 yards in a 34-31 win over Kansas City.
Jerome Bettis, Steelers, rumbled for 149 yards on 33 carries in the win over Philadelphia.
Willis McGahee, Bills, ran for a career-high 132 yards and a touchdown as Buffalo beat the Jets. He carried 37 times, tying Thurman Thomas for second most in team history, trailing only O.J. Simpson's 39.
Pittsburgh made certain there will be no unbeaten teams in the NFL this season. A week after they stopped New England's record 21-game winning streak, the Steelers handed Philadelphia its first loss, 27-3. Pittsburgh became the only team in NFL history to beat undefeated teams in consecutive weeks after each had won at least six games.
Arizona posted its first road win in 18 games, beating Miami, 24-23. The Cardinals had not won away from home since beating Carolina, 16-13, on Oct. 6, 2002.
Tiki Barber scored a touchdown for the sixth straight game in the Giants' 28-21 loss to Chicago.
Tim Brown was held without a catch, ending the third-longest streak in NFL history at 179 games. A reserve with Tampa Bay, the 38-year-old Brown played little in a 34-31 win over Kansas City. Jerry Rice's record of 274 consecutive games with a catch ended earlier this season.
Jets quarterback Chad Pennington missed most of the fourth quarter because of a bruised right shoulder. He will have more tests Monday, and said he expects to play next weekend against Baltimore.
Priest Holmes was out for most of the second half in Kansas City's loss to Tampa Bay. The All-Pro was hit on the right knee in the third quarter, but said he did not think the injury was too serious.
Bills right tackle Mike Williams injured his neck and was driven off the field in an ambulance during their victory over New York. He was walking around with a neck brace following the game and X-rays were negative.
Seattle cornerback Ken Lucas left the field on a cart after bruising his chest in a 42-27 win. He was expected to remain overnight in a San Francisco hospital.
Swing and a miss
Bill Gramatica missed an extra point in the first quarter, and that was the margin of defeat in Miami's 24-23 loss to Arizona. The Dolphins signed Gramatica on Friday because their two other placekickers were hurt.
Marshall Faulk moved into fourth place with 18,256 career yards, passing Barry Sanders (18,190).
Compiled from News and wire service reports.