Iroquois, ranked No. 2 among large schools, completed a perfect league season in ECIC Division III with a 56-25 rout of Cheektowaga.
Val Jacobs led the Chiefs with 20 points and seven rebounds while Eva Cunningham contributed 10 points, six assists and seven steals.
Iroquois finished 12-0 in ECIC III. The Chiefs end the regular season against No. 1-ranked small school Holy Angels in the Lockport Tournament Friday at 6 p.m. Angels is the only team to defeat Iroquois (17-1) this season.
Elsewhere in the division, Kristin Brunetto scored 15 points and Joelle Brunetto had 12 points and 10 rebounds in Depew's 51-27 rout of Maryvale. The Wildcats led, 28-6, at halftime.
Cheri White had 16 points and 12 rebounds and Karlyn Zielen had 12 points and 10 boards to lead Tonawanda over Amherst, 46-41. Beth Walsh's 13 paced the Tigers.
ECIC I: Clarence's Jamie Vaughan scored 30 points and had six assists and four steals in a 61-40 triumph over Williamsville North. April Reger had 12 rebounds for the Red Devils. Cheryl Kindzia led the Spartans with 11 points.
Hamburg was in charge all the way in a 59-32 victory over a winless, inexperienced Orchard Park team. Allison Barto had 15 points and Leah Colucci 10 points for the Bulldogs.
Heather Maziarz scored 12 points to lead Lancaster over Frontier, 50-32. Sara Ballard had 14 for the Falcons.
ECIC II: No. 3 large school Williamsville East wrapped up the regular-season division title with a 60-44 victory over No. 10 Sweet Home. Emily Skinner had 20 points and Lindsay Brent had 16 for the Flames, who stretched their winning streak to 16 and improved to 11-0 in division play with one game remaining. Timyra Hudson had 21 points and Rachel Rush 12 for Sweet Home.
Amanda Neamon had 17 points and Rachel Hicks 15 as No. 4 large school Pioneer pinned a 71-30 loss on Williamsville South. Brooke Matheis had 11 for the Billies.
Karyn Szafranski scored 17 points and passed off for six assists in No. 9 West Seneca West's easy 63-31 win over rival West Seneca East. Dawn Fronckowiak had 11 points and eight rebounds for the winners. Andrea Laux led WSE with 12 points.
ECIC IV: Laura Kozub scored 19 points in Alden's 47-38 victory over Holland. The outcome left the Bulldogs and East Aurora tied for first in the division with 9-1 records.
Leanne Gedraidits and Lindsey Broom each scored 13 for Holland.
East Aurora, No. 9 in the small schools poll, kept pace with Alden, defeating Lackawanna, 62-32. Heather Roughton led the Blue Devils with 14 points. Carissa Ferrucci and Rhiannon Polakiewicz had 12 each for the Steelers.
Andrea Deuser scored 13 points and Lindsay Szymenski 10 in JFK's 47-41 triumph over Cleveland Hill. Kim Griffin had 16 points and 14 rebounds for the Golden Eagles.
Niagara Frontier League: Kenmore East wrapped up a second straight unbeaten regular season in league play, building a 22-4 halftime lead on the way to a 35-25 victory over Lockport.
The Bulldogs, ranked No. 1 among large schools in Western New York, improved to 19-0 overall and are 16-0 in the NFL.
Maria Atti led Kenmore East with 19 points and 12 rebounds.
Erin Frieday scored a career-high 23 points as No. 6 large school Grand Island rolled past Niagara-Wheatfield, 64-18. Val Gasbarro added 12 points and Savannah Stolzenburg 11 for the Vikings, who limited the Falcons to just four points in the second half.
Rosie Ganschow had 16 points and 10 rebounds and Caroline Symes 15 points and 16 boards in North Tonawanda's 59-48 victory over Lewiston-Porter. Haley Mercer led the Lancers with 13.
Nichols, tied for No. 4 among small schools, rallied in the second half for a 63-53 triumph over Niagara Falls. Kristen Stone led the Vikings with 15 points. Mary Cohill had 13 points, seven rebounds and five steals. Chonita Palmer's 19 were tops for the losing Wolverines.
Canisius Cup: Shana Roulahac had 14 points and Jennifer Jackson 12 rebounds to lead da Vinci over Emerson, 36-25.
Niagara-Orleans League: Wilson, behind a 15-point, 14-rebound performance by Jamie Feagin clinched at least a tie for the league title with a 42-36 victory over visiting Albion. The Lakemen maintained their one-game lead over Starpoint. Each has one league game remaining.
Shinque Boose had 15 for Albion.
Dana Montazzoli and Ashley Powley each scored 13 points in Starpoint's 42-31 win over Roy-Hart. Powley had 17 rebounds. Grace Swick led the losing Rams with 16 points.
Sara Devoe poured in 25 points and pulled down 14 rebounds as Newfane downed Medina, 62-51. Clara Boise had 18 for the Mustangs.
Michelle Poodry had 26 points, 21 rebounds and seven steals in Akron's 50-39 win over Barker. Kay Lewis had 12 for Barker.
CCIAC I: No. 10 small school Gowanda averted an upset to last-place Falconer, squeaking by the Falcons, 51-49. Tina Homan had 19 points for the Panthers. Amanda Colburn scored 16 and Cheyenne Fralick had 12 points and 14 rebounds for Falconer.
Regular-season champion Olean, No. 7 among small schools, improved to 11-0 in league play with a 74-47 rout of visiting Dunkirk. Katie Estes and Katy Irving each had 14 points for the Huskies. Erin Bogardus led the Marauders with 15.
CCIAC II: A 16-point, 13-rebound performance by Amanda Harrington led Westfield over Cattaraugus/Little Valley, 46-31. Jenny Morrison had 14 rebounds and five assists and Lauren Wright had eight steals for the winners.
Melanie Lesczynski had 11 points and Jen Anderson 10 in Chautauqua Lake's 41-34 decision over Randolph. Megan Jones (12 points) and Jacquie Stimson (10 rebounds) stood out for Randolph.
CCIAC III: Ashley Kulju scored 20 points to lead Maple Grove over Ripley, 57-50. Kathy Baum had 19 points, 10 rebounds and five assists and Amy Eggleston 13 points and 14 rebounds in the loss.
IAC: Christina Mantione's 16 points led West Seneca Christian over St. Mary's School for the Deaf, 42-15. Karla Herdzik had 10 for the winners.
NFCAA: Stacy McClinsey scored a pair of key fourth-quarter baskets in Amherst Christian's 39-35 triumph over Central Baptist. Liz Ziarnowski led the winners with 14 points. Missy Tressley had 12 for Baptist.
Nonleague: Arielle Korczykowski scored 23 points to lead Lake Shore past Fredonia, 47-35. Ashley Scudder had 10 points and eight rebounds in a losing cause for the Hillbillies.
Angela Mecca's 14 points led North Collins past Eden, 49-37. Chrissy Gibbins led Eden with 14.