Kurt Warner, Rams, passed for 336 and four touchdowns in St. Louis' 41-20 victory in Atlanta.
Steve McNair, Titans, who only took a few snaps all week and didn't start because of a bruised sternum, replaced the injured Neil O'Donnell and threw an 18-yard TD pass with 1:25 left in Tennessee's 23-20 victory over Pittsburgh.
Brett Favre, Packers, passed for 277 yards and a touchdown and directed six other scoring drives in Green Bay's 29-3 victory over Arizona.
Elvis Grbac, Chiefs, threw two second-half TD passes as Kansas City overcame a 12-point deficit to beat Denver, 23-22. He connected with Derrick Alexander on a 22-yarder with 2:21 left.
Donovan McNabb, Eagles, was 20 of 32 for a career-high 222 yards and two TDs in Philadelphia's 21-7 victory in New Orleans.
Charlie Garner, 49ers, ran for a team-record 201 yards and a TD on 36 carries in San Francisco's 41-24 victory over Dallas. He also caught three passes for 34 yards.
Jamal Lewis, Ravens, ran for 116 yards and a touchdown in Baltimore's 37-0 victory over Cincinnati.
Wayne Chrebet, Jets, caught an 18-yard touchdown pass from running back Curtis Martin with 52 seconds remaining, giving New York a 21-17 victory over Tampa Bay.
Torry Holt, Rams, had TD catches of 85 and 80 yards in St. Louis' victory over Atlanta. He also had a 24-yard reception.
Tony Gonzalez, Chiefs, had career highs of 10 catches and 127 yards in Kansas City's victory in Denver. The tight end caught a 15-yard touchdown pass.
Keith Lyle and Grant Wistrom, Rams. Lyle scored on a 94-yard fumble return, and Wistrom had three of St. Louis' eight sacks against Atlanta.
Kurt Schulz, Lions, intercepted three passes in Detroit's 21-14 victory in Chicago.
William Thomas, Raiders, had two interceptions, including one he returned 46 yards for a touchdown, in Oakland's 36-10 victory over Cleveland.
Ryan Longwell, Packers, tied a team record with five field goals in Green Bay's victory over Arizona. He connected from 38, 47, 48, 37 and 22 yards.
Miami beat New England 10-3 to become the first team in NFL history to allow just one touchdown in its first four games. Miami has allowed 22 points, the fewest since Atlanta gave up 19 in its first four games in 1977. . . . San Francisco beat Dallas, 41-24, for the 49ers' second victory in 16 games. . . .Atlanta's Jamal Anderson has fumbled five times, and lost a league-high three.
The New York Jets are 4-0 for the first time since 1966, and have won an NFL-high eight straight regular-season games. . . . Jevon Kearse's NFL record of at least one-half sack ended at 13 games in Tennessee's victory in Pittsburgh. He left the game because of a hip flexor. . . . The Titans have won six straight against Pittsburgh, and are 17-2 against AFC Central rivals since 1998.
Denver's Terrell Davis played for the first time since spraining his left ankle in the season opener. He had a 24-yard run on his first carry against Kansas City and finished with 41 yards on six attempts.