Woodrow Dantzler ran for 220 yards and two long touchdowns, and completed 15 of 24 passes for 154 yards and another score as No. 11 Clemson beat Virginia, 31-10.
Jesse Palmer accounted for five touchdowns, four of them rushing, to tie a school record, as No. 3 Florida beat Kentucky for the 14th consecutive time, 59-31.
Neil Rose passed for 412 yards and three touchdowns, and Carl Morris set a school record with 220 yards receiving on 10 catches in Harvard's 42-37 victory over Brown.
Drew Brees was 33 for 49 passing for 409 yards and two touchdowns in No. 21 Purdue's 38-24 victory over Minnesota.
Jonathan Beasley scored a school-record five touchdowns as No. 4 Kansas State beat North Texas, 55-10.
Eric Crouch was 10 of 13 passing for 159 yards with five touchdowns, and also ran for 93 yards as No. 1 Nebraska beat Iowa, 42-13.
Tony Zimmerman was 12 for 15 for 262 yards and threw a school-record five touchdown passes as Duquesne beat Marist, 49-7.
L.J. McKanas rushed for 226 yards on a school-record 47 carries as Northeastern beat UConn, 35-27.
Rashaan Matthews threw five touchdowns to Darnerien McCants, four in the second half, as Delaware State beat Liberty, 42-25.
Anthony Thomas rushed for 228 yards and two touchdowns, including a 3-yard run with less than three minutes left, as No. 10 Michigan beat No. 19 Illinois, 35-31.
LaDainian Tomlinson ran for 140 yards and two touchdowns to lead No. 18 TCU to a 52-3 victory over Arkansas State. The Horned Frogs have won eight consecutive games, their longest winning streak since 1938 -- the last time they won a national championship.
Quarterback Jonathan Beasley scored a school-record five touchdowns as No. 4 Kansas State had 477 total yards in a 55-10 victory over North Texas. Kansas State has defeated Iowa, Louisiana Tech, Ball State and North Texas by a combined score of 212-20.
Ben Matthews tied an NCAA record with five interceptions as Bethel beat Gustavus, 14-13. Matthews tied the all-division record shared by eight players. Chris Butts of Worcester State was the most recent player to achieve it on Oct. 10, 1992.