Medina, Niagara-Wheatfield, Panama and Portville all won Saturday in the Section VI Federation to improve to 6-0 overall.
In Division II, Niagara-Wheatfield beat Grand Island, 50-19. Medina toppled Newfane, 34-9, in Division IV. Portville downed Silver Creek, 33-12, in Division VII, and Panama beat Chautauqua Lake, 29-15, in an interdivision game.
Orchard Park 24, Lockport 6: Andy Fried ran 11 times for 125 yards, including 15 yards for a touchdown, and Andy O'Hara passed for a touchdown and intercepted two passes to lead the Quakers. Joe Jenkins, who totaled 108 yards on the ground, scored for Lockport on a 31-yard run.
Frontier 46, W. Seneca East 0: Rick O'Neal led the Falcons with 145 rushing yards and three touchdowns in a romp. O'Neal scored on runs of 31, 31 and 35 yards, and Joe Clouden added 111 yards and a rushing touchdown. Quarterback Danny Conrad was 7 of 7 for 106 yards with two touchdowns for Frontier.
N. Tonawanda 37, Hamburg 0: Aaron Day rushed for 142 yards, including a 70-yard touchdown run, as the 'Jacks improved to 5-1 overall. Todd Warmington added touchdown runs of 3 and 28 yards. Chris Kitcho had two of his team's eight sacks. On the ground, the 'Jacks outgained the Bulldogs, 328-7.
Sweet Home 15, Clarence 14: The Panthers overcame a 14-3 third-quarter deficit to edge the Red Devils. Clarence was plagued by five turnovers, including four interceptions on its last four possessions. Durrell Hatch returned an interception to the Clarence 4-yard line to set up Sweet Home's first touchdown. Hatch also scored the game-winner on a 1-yard run to finish with 80 yards on 19 carries.
Niagara-Wheatfield 50, Grand Island 19: The Falcons, ranked No. 1 among Western New York large schools in The Buffalo News polls and No. 2 in the state, rushed for 404 yards. Nick Condino scored three rushing touchdowns and returned an interception 16 yards for another score. Rashad Evans rushed 15 times for 177 yards for the Falcons. Tom Winarske and quarterback Brad Greenfield hooked up on a pair of touchdown passes for the Vikings, the No. 4-ranked large school.
Lew-Port 20, Kenmore East 14 OT: Matt Gualtieri scored on a 1-yard run in overtime as the Lancers won for the first time. Gualtieri also had an 80-yard run to open the scoring. Ryan Myers recovered a fumble in overtime to help Lew-Port keep Kenmore East at bay. The Lancers tied the game in the third quarter when Anthony Cerminara returned a fumble for a touchdown. Ryan Kirbis had touchdown passes to Mike Atti and Dave Krieger for East.
West Seneca West 20, Lake Shore 13: Sean Donaldson scored on a 7-yard run with 2:30 left in the game, highlighting a nine-play, 76-yard drive for the Indians. Lake Shore drove to the West 14-yard line with 54 seconds to go, but defensive back Ian Riddick intercepted the ball in the end zone. Kurt Miller had 19 tackles and Mike Dziak added 11 tackles plus 2 1/2 sacks for West. The winless Eagles scored when Dominic Calandra passed for a touchdown and rushed for another.
Medina 34, Newfane 9: Lionel Rhim and Jamie Duffina packed a potent one-two backfield punch as the Mustangs stayed undefeated. Rhim had 14 carries for 134 yards and two touchdowns, and Duffina had 10 carries for 130 yards and two scores. Joe Sands led Medina with six tackles and a blocked kick. The Mustangs are ranked No. 12 in the state in Class B and No. 2 among Western New York small schools.
Starpoint 25, Maryvale 15: Steve Wright scored on runs of 3 and 9 yards and finished with 113 rushing yards as the Spartans earned their first win. Jason Suita added 100 yards and an 18-yard touchdown run. Maryvale's Bryan Kaczmanski ran for one touchdown and passed for another.
Southwestern 51, Fredonia 27: J.C. Matteson rushed for 211 yards on 29 carries and scored four times to lead the Trojans. His touchdown runs covered 3, 19, 1 and 21 yards. Dusty Carlson was 9 of 14 passing for 106 yards with two touchdowns and also returned an interception 35 yards for a score. Mike Cerri passed for 323 yards and three touchdowns for Fredonia.
Olean 12, Iroquois 7: Steve Gold's 45-yard touchdown pass to J.R. Kemp in the fourth quarter was the difference for the Huskies. Ike Simon rushed for 89 yards and a had 50-yard scoring run for Olean, which got 118 passing yards from Kevin Gunther.
JFK 24, Cleveland Hill 20: Matt Tyx ran for a pair of fourth-quarter touchdowns to help the Bears down the winless Eagles. Tyx, who finished with 81 yards, had scored earlier on a 1-yard run. Cleveland Hill's Myron Lee passed for two TDs and ran for a third.
Portville 33, Silver Creek 12: John Debarbieri ran for 150 yards and a 3-yard touchdown for the No. 6 small school Panthers. Adam Babcock added a 1-yard touchdown run for Portville.
Ellicottville 54, Little Valley 8: Running back Keith Boldt scored three touchdowns and Darrell Hurlburt rushed for 137 yards on 18 carries as the Eagles cruised. Mike Young had just two carries, but he scored on both with runs of 21 and 31 yards. Little Valley running back Harry Ginnery had 92 all-purpose yards. Brandon Brown scored Little Valley's touchdown on a 10-yard pass from Craig Learn.
Eden 22, Cassadaga Valley 6: The Raiders won for the first time behind two touchdowns from Don Jenco. Jared Engle returned an interception 53 yards for a score and Bill Osinski added 13 tackles and an interception for Eden.
Pine Valley 44, Sherman 0: Brian Lucas passed for two touchdowns and ran for a third as the Panthers overpowered the Wildcats, gaining a 31-0 advantage by halftime.
Forestville 53, West Valley 0: Larry Croft scored five touchdowns on just nine carries as the Hornets blanked the Wildcats. Josh Cross added a 78-yard interception return and a 32-yard fumble return.
Cattaraugus 28, Frewsburg 12: Quarterback Mike Bowers threw four touchdown passes to lead the Big Red. Paul Paddock rushed for 108 yards and caught a TD pass. For Frewsburg, Bill Prince had 18 carries for 140 yards, an interception and 12 tackles.
The Panama at Chautauqua Lake game was not reported to The Buffalo News.