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Cleveland BioLabs has reached an agreement with the U.S. Food and Drug Administration on the shape of the clinical studies the Buffalo life sciences company needs to do to win approval for a key anti-radiation sickness drug. The agreement, outlined in an advice letter from the FDA, is a significant development for Cleveland BioLabs because some of its key federal funding s…

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Wired.com has an interesting read about "How Nerf Became the World’s Best Purveyor of Big Guns for Kids." For [product design manager Brian] Jablonski, blasters are the most satisfying Nerf products to create, each one requiring the participation of about 15 Hasbro designers, engineers, marketers, product development specialists, model makers, model painters, and…

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Autumn's a great time to fall for apple appeal, with cooler temperatures setting the stage for the fruit to star in gently steaming pies and alongside fragrant roasts. Or you could drink your apple a day, the fermented way. Hard cider, which came to the United States with the Pilgrims but was lost in a sea of sweet, unfermented juice after Prohibition, has been making a co…

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A customer with smartphone in hand walks into Runner's Roost, peruses the wall of footwear, snaps pictures and scans barcodes and bolts out.What just happened?It's called "showrooming," and it is starting to hurt some businesses. Customers visit a store, examine merchandise, touch it and sometimes even try it on, then look online for a cheaper price."It's like we're doing …

CAMBRIA . Ridge Road & Burch Road, Stephen T. Winkiewicz to Debra Jones; Joseph Jones, $146,000. . Budd Road, Calvin F. Gnage; Candace A. Gnage to Paul Siuta, $110,000. HARTLAND . Ridger Drive, Kurt J. Koch; Marjorie L. Koch to Emily A. Yotter; Daniel F. Yotter, $63,600. LEWISTON . Mohawk St., Patricia A. Crowley to Linda J. Moscati, $143,000. . Country Club Trail & Lilac …

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The owners of One HSBC Center are seeking help from national land-use and building-use experts about what to do with anticipated vacant space in Buffalo's tallest tower, space that will open up if the major tenant ends up leaving in the next year. Seneca One Realty LLC, the New York-based investor group that owns the 38-story tower, has "been in touch" with the Urban Land …

Continuing their downward march, bankruptcy filings in Western New York again fell in August, showing no signs of having reached a new floor. New bankruptcy cases fell 10.6 percent from a year earlier in the Buffalo and Rochester courts, to 538 filings from 602 in August 2011, according to new statistics from the U.S. Bankruptcy Court for the Western District of New York. …

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Al Scibetta has a clear view of Ellicott Street from his office at the front of Copier Fax Business Technologies. Having his business downtown matters to him. "This might be just me, but I believe when you're located in the central business district of a city, it denotes strength, it denotes your commitment to the region," said Scibetta, company president. Scibetta has als…

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A customer with smartphone in hand walks into Runner's Roost, peruses the wall of footwear, snaps pictures and scans barcodes and bolts out. What just happened? It's called "showrooming," and it is starting to hurt some businesses. Customers visit a store, examine merchandise, touch it and sometimes even try it on, then look online for a cheaper price. "It's like we're doi…

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Joblessness among women is having a ripple effect on the child care industry, according to an article on Bloomberg.com: Cost-conscious households are one reason employment in the childcare industry has dropped 1.8 percent since the recession ended June 2009, even as total U.S. payrolls increased 2.1 percent. Jobs in the sector hover at levels of five years ago as unemploye…

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Ulrich's Tavern has officially reopened. A month after being abruptly shut down by the state for back taxes, the iconic Buffalo tavern and restaurant held a bar-only reopening party Tuesday sponsored by Flying Bison Brewery. Ulrich's filed for bankruptcy Aug. 23, with a list of creditors including the state Department of Taxation & Finance, which was owed $205,000, and the…

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Jerry Petrotto couldn’t believe his luck. The Williamsville man had attended a Get Motivated! seminar at First Niagara Center with some colleagues from work, attracted by the low $1.95 ticket price and top-notch motivation speakers: at First Niagara Center in June, attracted by powerhouse motivational speakers such as former presidential nominee Steve Forbes, former Bills …

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The Buffalo show was the last for the Get Motivated seminar series. The Florida company that hired celebrities including Rudy Giuliani and Colin Powell for motivational events that filled arenas around the U.S. has closed, leaving lawsuits complaining of unpaid bills. The closing came after the seminar failed to draw a door-buster crowd in Buffalo in June. The seminars has…

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Enabling minority and disadvantaged small businesses to gain access to more government contracts is a critical way for the federal government to create new jobs and boost the economy, an Obama administration official said Thursday.Marie C. Johns, deputy administrator of the U.S. Small Business Administration, was touring a Native American-owned construction firm in Lackawa…

Tops Friendly Markets launched a new school fundraising program that allows BonusCard and BonusPlus users to rebate a portion of certain purchases to the schools of their choice.Shoppers who sign up for the Tops in Education program can choose to link their card account to a participating elementary, middle or high school. Whenever that shopper buys Tops, Full Circle or To…