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Buffalo drug development company Athenex Inc. is launching an early-stage clinical trial for an oral form of a drug that potentially could be used as part of a treatment for gastric cancer. The Phase 1b clinical trial of its Oraxol drug, administered in conjunction with another drug, ramucirumab, is underway, with a patient recently receiving the first dose of the drug,…

The Lockport Housing Authority and Buffalo Geothermal LLC of Cheektowaga are receiving an award for their installation of a geothermal heating and cooling system at the Autumn Gardens apartment complex on East High Street. The equipment, installed in 2015, replaced an electric heating system in the 72-unit complex that dated from 1972. The system provides year-round c…

The former Lord Amherst Hotel, reborn as the "upper upscale" Reikart House following a nearly $20 million renovation, is now open to guests. The owners of the 92-room, boutique hotel at 5000 Main St. in Snyder held a soft opening Thursday. The hotel that opened in 1962 as the Lord Amherst motor lodge is the first in New York state to operate as part of Marriott Internat…

The Ford Friendship Express program is now taking applications from nonprofits and community groups for its 2017 edition. The program awards one or more free Ford vans a year. To be eligible, an organization must reside in Erie, Niagara, Orleans, Wyoming, Chautauqua, Cattaraugus and Allegany counties. The application deadline is Sept. 29. The winner, or winners, will be…

The Buffalo Niagara region's sluggish job market didn't heat up in June. The region added jobs at a 0.5 percent annual pace – three times slower than the nationwide increase – during June, extending a stretch of tepid hiring that began in March and has continued for four months, the state Labor Department reported Thursday. The job growth was even slower during J…

The Town of Amherst is one step closer to preserving as parkland 60 acres of green space that were the subject of a bruising legal fight with a developer who wanted to build a subdivision there. The land, largely made up of wetlands, was as far back as 2000 the intended site of the 57-home, Gramercy Park Estates subdivision between Casey and North French roads, west of …

KeyCorp credited the First Niagara deal with helping deliver solid results in the second quarter. "It was another strong quarter for Key, demonstrating the value of our First Niagara acquisition and the core momentum we have built in our company," said Beth Mooney, the bank's chairman and CEO, as the bank released its earnings on Thursday. Cleveland-based Key report…

CNB Financial Corp., which has a local presence through Bank on Buffalo, recorded a 64 percent increase in its second quarter profits, to $6.7 million. Pennsylvania-based CNB's net interest income from making loans and taking deposits increased nearly 19 percent, to $23 million. Its non-interest income from sources like fees increased 6 percent, to $5.1 million. CNB…

It's the end of an era on Elmwood Avenue. Urban will close its doors Aug. 27 after 25 years on the Elmwood strip. The name of the store, at 736 Elmwood Ave., has changed over the years to correspond with its changing retail focus. When it opened in 1992, it was called Urban Surfer after the surf and skate gear and clothing it sold. When it shifted its focus to snowboard…

The exodus continues at SolarCity's California executive suite, just as hiring starts to ramp up at its sprawling solar panel factory in Buffalo. Only eight months after Tesla Inc. acquired SolarCity, all of the rooftop solar installer's highest-ranking executives have either left or plan to leave the electric vehicle-maker, including co-founders Lyndon and Peter Rive. …

Many businesses are taking a wait-and-see approach about decisions coming out of Washington, before taking on new debt through loans, a top M&T Bank executive said Wednesday. "We're not dire on the economy by any stretch, but I would say there is some uncertainty and some cautiousness," Darren J. King, M&T Bank's chief financial officer, said as M&T release…

Amid other changes, two new stores are coming to Walden Galleria. BoxLunch, a novelty gift shop and apparel store, will open by the end of summer. The store will fill 1,798 square feet on the upper level near J.C. Penney. Similar to Hot Topic or Spencer's, BoxLunch sells licensed and non-licensed pop culture merchandise such as "Game of Thrones" T-shirts, Harry Potte…

Buffalo Canvas opened its doors at 1882 Hertel Ave. earlier this month. The wall art and gift shop is the retail arm of an art and design company that has been in business for five years.  It provides fine art, printing services, photography, design and installation. Its clientele include photographers, artists, commercial and small businesses, interior designers and …

Gymboree, a children's clothing retailer, will close its store at Walden Galleria. Crazy 8, a children's retail brand owned by Gymboree, will also close stores at the Boulevard Mall and Walden Galleria. No closing dates have been announced, but liquidation sales began Tuesday. San Francisco-based Gymboree is closing 350 stores across the nation as part of a bankruptc…

Tompkins Bank of Castile's headquarters in Batavia overlooks Main Street, where M&T Bank and KeyBank have branches practically across the street. So Tompkins Bank of Castile knows all about the tough competition it will face on a larger scale in the Buffalo market, where it is preparing to open a branch. M&T dominates the Buffalo area in deposit marke…