Some important members of the Bills coaching staff have relatively recent experience facing the Jaguars.
Last year, offensive coordinator Rick Dennison was the offensive coordinator for the Broncos when they traveled to Jacksonville and emerged victorious 20-10. As the defensive coordinator for the Panthers, Sean McDermott opened the 2015 regular season against Blake Bortles and Co. at home and won 20-9.
While the Jaguars aren't the same team — especially on defense — as they were the past two years, let's examine each respective unit in both matchups. As you'll notice, the play of Bortles was critical in these specific contests against the Broncos and Panthers.
December 4, 2016 - Broncos 20, Jaguars 10
Denver's offense scored 13 points in this game, as cornerback Bradley Roby intercepted Bortles and ran it back for a touchdown.
Rookie Paxton Lynch started for the Broncos, and he completed 12 of 24 passes for 104 yards with two interceptions. That equated to a passer rating of 61.8. He also ran twice for 11 yards.
Kapri Bibbs, Devontae Booker, and Juwan Thompson combined for 89 rushing yards on 25 carries with one touchdown.
Clearly, with Lynch under center, the Broncos had problems moving the football against a Jaguars defense on the rise. Denver went 1-13 on third down and averaged just 3.8 yards per play in this defensive struggle.
September 13, 2015 - Panthers, 20, Jaguars 9
Against Carolina's defense, Bortles went 22 of 40 for 186 yards with one touchdown pass and two interceptions. That equated to a quarterback rating of 54.5.
T.J. Yeldon and Denard Robinson combined for 70 yards on 17 carries, and Bortles rushed for 26 yards on four carries of his own.
The Jaguars went 3-12 on on third down and averaged 4.0 yards per play.
One of Bortles' interceptions was returned 30-yards for a touchdown by Josh Norman, which gave Carolina a 17-9 lead in the third quarter.