The Bills got off to a good start in the first quarter, jumping out to a 7-0 lead while Miami sent its backup quarterback into the game.
After forcing a three-and-out to open the game, the Bills drove 72 yards in seven plays for a touchdown, capped by Tyrod Taylor's 26-yard touchdown pass. Tight end Nick O'Leary got behind the defense on the play-action bootleg and was wide open in the end zone. CBS cameras showed O'Leary's grandfather, golf legend Jack Nicklaus, in attendance at the game.
Dolphins quarterback Jay Cutler started what could be the final game of his career, but was replaced by backup David Fales after one drive. The Dolphins wanted to get a look a Fales, the former sixth-round pick, to see if he would be worth keeping around as a backup next year when starter Ryan Tannehill returns from injury.
Fales drove the Dolphins into Bills' territory on his first drive, but cornerback Leonard Johnson broke up his fourth-down pass from the Bills' 15-yard line. LeSean McCoy ran four times for minus-6 yards in the quarter.
Scoreboard watching: The Bills need help to make the playoffs, and they were looking for losses from the Ravens, Titans and Chargers. After one quarter, the Ravens were losing to the Bengals 7-0, the Titans and Jaguars were tied 0-0, and the Chargers were tied with the Raiders 0-0.