Let's examine the most crucial one-on-one matchups in the Bills' game against the Bengals in Cincinnati, a critical contest before Buffalo's bye week.
Stats courtesy of Pro Football Focus.
Bills' biggest disadvantage
Geno Atkins vs. Eric Wood
Atkins poses a gigantic problem for any interior offensive line he faces. He possesses elite quickness, leverage, strength, and pass-rushing technique to win in a multitude of ways.
As I referenced in my advanced-stats preview of the Bengals, the veteran defensive tackle has 19 quarterback pressures through four games. He's generated those pressures on 112 pass-rush snaps. That equates to a Pass-Rush Productivity of 13.2, the fourth-highest figure among 79 qualifying defensive tackles.
He's a handful.
Meanwhile, Bills center Eric Wood has had some issues as a pass-protector through four games. He's surrendered four pressures (two hits, two hurries) on 127 pass-blocking snaps. While that may not seem like a high rate of pressures allowed, it's the 13th-best Pass-Blocking Efficiency score (97.6) out of 33 qualifying centers. Not bad but not great.
Beyond that, Wood has a run-blocking grade of 49.7, the eighth-lowest grade out for 34 qualifying centers in that area, and Atkins is a stellar run-defender. His grade stopping the run is 81.6, the 13th-highest run-defending grade out of 113 qualifying interior defensive linemen.
Wood needs to have one of his best games to keep Atkins at bay.
Bills' biggest advantage
Micah Hyde / Jordan Poyer vs. Andy Dalton's deep passing
Through four games in the 2017 season, Dalton has completed 3 of 12 attempts for 109 yards with no touchdowns and no interceptions on passes made beyond 20 yards, which is good for a passer rating of 64.9. That's the 10th-worst rating among 32 qualifying quarterbacks.
Buffalo's safety tandem of Hyde and Poyer have been integral parts of Buffalo's defense defending the deep ball extremely well. Josh McCown, Cam Newton, Trevor Siemian, and Matt Ryan have combined for five completions on 16 attempts for 142 yards with zero touchdowns and three picks on throws made 20 yards or more downfield against the Bills. That's a passer rating of 25.5.
Hyde has two of those interceptions. Poyer has the other.
Dalton will have his work cut out for him trying to complete passes down the field against the Bills on Sunday.
Best one-on-one matchup
Tre'Davious White vs. A.J. Green
While they may not matchup with each other on every pass play for the Bengals, Green and White make for a tremendous wideout-cornerback battle when they do align together before the snap. Green has been an elite wide receiver for years now and presents a major challenge for the rookie corner.
White has been tremendous early in his NFL career. He's leading the league in pass breakups, has snagged an interception, and quarterbacks have a 53.7 passer rating on throws in his target area.
Green has the third-highest receiving grade among wideouts (86.8). White's coverage grade is the fifth-highest among cornerbacks (88.4).