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Carlos Zambrano shook off a cramp in his pitching arm, then shut down the Milwaukee Brewers.

Zambrano (1-0) pitched one-hit ball into the eighth and had two singles and an RBI to help the Chicago Cubs deal Milwaukee its first loss of the season, 4-0.

Zambrano gave up only a two-out line single in the second inning to Russell Branyan, and shut down a Brewers lineup that scored 25 runs in the first three games. He struck out six and walked two while outpitching fellow opening-day starter Ben Sheets (1-1).

But after throwing just one pitch to the second hitter of the game, Junior Spivey, Zambrano stepped off the mound, pointed to his pitching arm and signaled for Cubs trainer Mark O'Neal.

Zambrano was allowed three additional warm-up tosses. He then struck out Spivey on the next three pitches and cruised until being relieved by Chad Fox with one out in the eighth.

"It happens to me all the time," Zambrano said, referring to the cramp. "I have to drink more water. It has nothing to do with my elbow or shoulder."

Cubs manager Dusty Baker, whose team snapped a three-game losing streak, said the same thing happened to Zambrano in a game last season.

"I'm just glad it was muscle and nothing else," Baker said. "He was throwing great from the beginning. He hit well, he ran well, he did everything well today.

Around the horn

Elsewhere in the American League, Hank Blalock and Richard Hidalgo each hit two-run homers in the ninth inning to lift the Rangers to a 7-6 win over the Mariners. . . . Josh Phelps and Aubrey Huff hit three-run homers as the Devil Rays roughed up the Athletics, 11-2. . . . Carl Everett, Timo Perez and Paul Konerko homered as the White Sox beat the Twins, 8-5.

Elsewhere in the National League, Pat Burrell was 4 for 5 with a three-run home run and five RBIs, and Bobby Abreu also homered for the Phillies in a 10-4 victory over the Cardinals. . . . Michael Tucker hit his first career grand slam with two outs in the eighth inning to lift the Giants over the Rockies, 4-2. . . . Jose Guillen hit a two-out home run in the 10th inning, and Ryan Church and Vinny Castilla also hit solo homers to help the Nationals defeat the Marlins, 3-2. . . . Jose Vizcaino's pinch-hit double with no outs in the bottom of the ninth scored Willy Tavares, who had singled, and gave the Astros a 4-3 win over the Reds.

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