Peyton Manning, Colts, broke Johnny Unitas' franchise record with 404 yards passing and two touchdowns in a 27-19 victory over the San Diego Chargers. He completed 29 of 54 passes.
Kurt Warner, Rams, threw for 275 yards and three touchdowns and also ran 5 yards for another score as St. Louis defeated Atlanta, 35-7.
Brett Favre, Packers, was 24 of 39 for 304 yards in a 23-20 victory over Minnesota. He was 6 of 7 on a final drive that finished with his 23-yard TD pass to Corey Bradford.
Tshimanga Biakabutuka, Panthers, rushed for 132 yards on just eight carries, including TD runs of 62 and 67 yards in Carolina's 27-3 victory over Cincinnati. Both runs were longer than the previous team record of 53 yards.
Mike Alstott, Buccaneers, rushed for a career-high 131 yards and scored on a 28-yard run in the first quarter in Tampa Bay's 13-10 victory over Denver.
Marvin Harrison, Colts, caught 13 passes for 196 yards and a touchdown in Indianapolis' 27-19 victory over San Diego.
Jimmy Smith, Jaguars, caught 10 passes for 129 yards and a touchdown in Jacksonville's 20-17 loss to Tennessee.
Tim Brown, Raiders, caught nine passes for 121 yards and a touchdown in Oakland's 24-17 victory over Chicago.
Todd Peterson, Seahawks, kicked a club-record five field goals in Seattle's 29-10 victory over Pittsburgh.
Stephen Davis, the NFL's leading scorer with five touchdowns going into the day, had three more TDs on short runs in Washington's 27-20 victory over the New York Jets. . . . Stoney Case was Baltimore's fourth starting QB in 13 games. . . . Denver is the first defending Super Bowl champion to begin a season with three straight losses in a non-strike year. The New York Giants started 0-5 in 1987 following a Super Bowl championship, but three of those losses were with replacement players.
Denver's Terrell Davis, who had more than 2,000 yards rushing last season, failed to gain 100 yards for the third straight game, picking up 53 on 19 carries in the Broncos' 13-10 loss to Tampa Bay. . . . Pittsburgh, two weeks after defeating Cleveland, 43-0, trailed Seattle, 26-0, at halftime on the way to a 29-10 loss. . . . Trent Dilfer bounced back from poor performances in Tampa Bay's first two games to complete 15 of 18 passes for 135 yards against Denver. He had no major mistakes after throwing five interceptions and losing a fumble in the Bucs' first two games.
Rookie cornerback Antuan Edwards intercepted two of Randall Cunningham's passes and returned one of them 26 yards for a touchdown as Green Bay defeated Minnesota, 23-20. . . . Tennessee intercepted three of Mark Brunell's passes in the Titans' 20-19 victory over Jacksonville, including a game-saving pick in the end zone by Samari Rolle with the Jaguars in easy field goal range in the final two minutes. . . . Merton Hanks scored on a 23-yard interception return to give Seattle its first points against Pittsburgh in a 29-10 victory. It was the first of the Seahawks' five interceptions. . . . Chicago recovered five Oakland fumbles in the Raiders' 24-17 victory.
Kenard Lang had three of Washington's six sacks in its 27-20 victory over the New York Jets. . . . Neil Smith had two of Denver's seven sacks, giving him 101 in his career.Struggling
The four teams in last season's conference championship games are a combined 1-11. The Denver Broncos, Atlanta Falcons and New York Jets are 0-3, and Minnesota is 1-2. . . . Cleveland rookie Tim Couch was 13 of 32 passing for 123 passing yards and fumbled to set up a Baltimore touchdown in the Browns' 17-10 loss to the Ravens. . . . In their first six possessions on the way to a 31-21 loss to Kansas City, the Detroit Lions were sacked three times, had a pass batted down, were penalized twice and punted five times. . . . Cincinnati's Doug Pelfrey missed three field goals in the Bengals' 27-3 loss to Carolina.
Charlie Rogers scored on a 94-yard punt return for Seattle in a 29-10 victory over Pittsburgh. . . . Michael Dumas blocked a punt for San Diego that Darryll Lewis recovered in the end zone in the Chargers' 27-19 loss to Indianapolis. . . . Kevin Johnson had an 81-yard kickoff return to set up a field goal in the New York Jets' 27-20 loss to Washington. . . . John Jett had a career-best 62-yard punt for Detroit in the Lions' 31-21 loss to Kansas City. . . . Chicago's Glyn Milburn returned an Oakland kickoff 92 yards to the 9, setting up a Bears touchdown.
Atlanta quarterback Chris Chandler reinjured the right hamstring that kept him out of Monday night's loss at Dallas. Chandler, who was 5 for 9 for 28 yards and an interception in the 35-7 loss to St. Louis, was injured late in the first half without contact while scrambling. . . . Ki-Jana Carter, the oft-injured first overall pick in the 1995 draft, dislocated his right kneecap in the first quarter of Cincinnati's 27-3 loss to Carolina.